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Recommended positive controls: mouse muscle.
Predicted reactivity: Mouse (95%), Rat (96%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta-dystrobrevin; DTN-B; Dystrobrevin beta; dystrobrevin, beta; mDTN-B
基因别名: DTNB
UniProt ID: (Human) O60941, (Mouse) O70585
Entrez Gene ID: (Human) 1838, (Mouse) 13528