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Invitrogen
DTNBP1 Polyclonal Antibody
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DTNBP1 Antibody (PA5-102450) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded DTNBP1 in mouse spleen tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with DTNBP1 polyclonal antibody (Product # PA5-102450) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102450
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DTNBP1(Accession Q96EV8), corresponding to amino acid residues Q284-T334.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DTNBP1.
靶标信息
Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; distrobrevin binding protein 1; DKFZp564K192; DTBP1; Dysbindin; Dysbindin-1; Dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; Hermansky-Pudlak syndrome 7 protein homolog; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy
基因别名: 5430437B18Rik; AW048963; BLOC1S8; DTNBP1; dysbindin; My031; Sdy
UniProt ID: (Mouse) Q91WZ8, (Rat) Q5M834
Entrez Gene ID: (Mouse) 94245, (Rat) 641528
positive regulation of neurotransmitter secretion
organelle organization
muscle organ development
blood coagulation
anterograde axonal transport
positive regulation of gene expression
regulation of dopamine secretion
neuron projection development
actin cytoskeleton reorganization
anterograde synaptic vesicle transport
neuron projection morphogenesis
response to stimulus
platelet dense granule organization
regulation of dopamine receptor signaling pathway
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