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Invitrogen
DUSP18 Polyclonal Antibody
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产品信息
PA5-65657
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: APSCAFPVQFR QPSVSGLSQI TKSLYISNGV AATN
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 71%.
靶标信息
DUSP18 (E.C 3.1.3.16), a novel DSP, is a member of highly conserved protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation and mitogenic signal transduction. DUSP18 is a low molecular weight protein consisting of conserved N-terminal DSP domain but lacks CH2 domain. Studies reveal that DUSP18 is a unique DSP that interacts and dephosphorylates SAPK/JNK. Reports suggest it inhibits SAPK/JNK invivo and might serve an important role in the regulation of SAPK/JNK pathway. Northern Blot analysis detected a ubiquitous expression of DUSP18.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bK963H5.1; Dual specificity protein phosphatase 18; LMW-DSP20; Low molecular weight dual specificity phosphatase 20
基因别名: DSP18; DUSP18; DUSP20; LMWDSP20
UniProt ID: (Human) Q8NEJ0
Entrez Gene ID: (Human) 150290
