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Immunogen sequence: MCDRKAVIKNA DMSEEMQQDS VECATQALEK YNIEKDIAAH IKKEFDKKYN PTWHCIV
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1, 200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 8 kDa dynein light chain; cytoplasmic dynein light polypeptide; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1MGC126138; Dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; H LC8; LC8-type 1; MGC126137; MGC126138; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase
基因别名: DLC1; DLC8; DNCL1; DNCLC1; DYNLL1; HDLC1; LC8; LC8a; PIN
UniProt ID: (Human) P63167
Entrez Gene ID: (Human) 8655