Invitrogen

DYNLL1 Recombinant Rabbit Monoclonal Antibody (SD08-04)

Name: DYNLL1 Recombinant Rabbit Monoclonal Antibody (SD08-04)
Brand: Invitrogen
SKU: MA5-32384

查看其他12个DYNLL1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

DYNLL1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

DYNLL1 Antibody (MA5-32384) in ICC/IF

Immunocytochemical analysis of DYNLL1 in HepG2 cells using a DYNLL1 Monoclonal antibody (Product # MA5-32384) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

DYNLL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Immunogen image

Immunogen Image DYNLL1 Recombinant Rabbit Monoclonal Antibody (SD08-04)

产品信息

MA5-32384

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

SD08-04

抗原

Synthetic peptide within Human DYNLL1 aa 1-50

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2809664

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1, 200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: 8 kDa dynein light chain; 8kD LC; 8kDa LC; cytoplasmic dynein light polypeptide; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1MGC126138; dynein LC8; Dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; H LC8; LC8-type 1; MGC126137; MGC126138; mPIN; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase

查看更多收起

基因别名: 8kDLC; DLC1; DLC8; DNCL1; DNCLC1; DYNLL1; HDLC1; LC8; LC8a; PIN

查看更多收起

UniProt ID: (Human) P63167, (Rat) P63170, (Mouse) P63168

查看更多收起

Entrez Gene ID: (Human) 8655, (Rat) 58945, (Mouse) 56455

查看更多收起

功能

motor activity protein binding protein C-terminus binding protein domain specific binding enzyme inhibitor activity enzyme binding nitric-oxide synthase regulator activity protein homodimerization activity microtubule or microtubule-binding cytoskeletal protein

参与通路