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Invitrogen
Dabigatran (Idarucizumab Biosimilar) Recombinant Humanized mouse Monoclonal Antibody
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Dabigatran (Idarucizumab Biosimilar) Antibody (MA5-41998) in SDS-PAGE
SDS-PAGE analysis of the recombinant Pradaxa (Dabigatran Etexilate Mesylate) dabigatran etexilate mesylate protein expressed in CHO cells using a Dabigatran (Idarucizumab Biosimilar) monoclonal antibody (Product # MA5-41998). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-41998
产品规格
种属反应
Chemical
宿主/亚型
Artificial Control
/ IgG1, F(ab), kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Pradaxa (Dabigatran Etexilate Mesylate) dabigatran etexilate mesylate
偶联物
形式
Liquid
浓度
2.53 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
30mM histidine/PBS, pH 6.0, with 10% sucrose, 60ppm Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Dabigatran is an oral direct thrombin (factor IIa) inhibitor used as an anticoagulant. It works by selectively and reversibly blocking thrombin, preventing the conversion of fibrinogen to fibrin and thereby reducing blood clot formation. Dabigatran is commonly prescribed for stroke prevention in patients with nonvalvular atrial fibrillation and for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is administered as the prodrug dabigatran etexilate and does not require routine coagulation monitoring. An approved reversal agent (idarucizumab) is available for emergency situations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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