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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Desmoglein 2 (DSG2) Antibodies

          Invitrogen

          Desmoglein 2 (DSG2) Polyclonal Antibody

          1 篇参考文献
          查看其他24个Desmoglein 2 (DSG2)抗体

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          说明书
          实验方案
          问题与答案
          技术支持
          说明书
          实验方案
          问题与答案
          技术支持

          Cite Desmoglein 2 (DSG2) Polyclonal Antibody

          • 抗体检测数据 (6)
          Desmoglein 2 (DSG2) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Desmoglein 2 (DSG2) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 6

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          Desmoglein 2 (DSG2) Antibody (PA5-79171) in ICC/IF

          Immunocytochemistry analysis of DSG2 using anti-DSG2 antibody (Product # PA5-79171) . DSG2 was detected in a section of MCF-7 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-DSG2 antibody (Product # PA5-79171) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit Ig... View More {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          Desmoglein 2 (DSG2) Antibody in Immunocytochemistry (ICC/IF)
          Desmoglein 2 (DSG2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Desmoglein 2 (DSG2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Desmoglein 2 (DSG2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Desmoglein 2 (DSG2) Antibody in Western Blot (WB)
          Desmoglein 2 (DSG2) Antibody in Flow Cytometry (Flow)
          Desmoglein 2 (DSG2) Polyclonal Antibody

          产品信息

          PA5-79171

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          0.1-0.5 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          0.5-1 µg/mL
          -

          免疫细胞化学 (ICC/IF)

          2 µg/mL
          查看1篇已发表文章 1篇已发表文章

          流式细胞分析 (Flow)

          1-3 µg/1x10^6 cells
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          已发表种属

          Mouse

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2 (1104-1118aa STRVTKHSTVQHSYS).
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Lyophilized

          浓度

          500 µg/mL

          纯化类型

          Antigen affinity chromatography

          保存液

          PBS with 5mg BSA

          内含物

          0.05mg sodium azide, 0.05mg thimerosal

          保存条件

          -20°C

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2746287

          产品详细信息

          Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

          Positive Control - WB: human Hela whole cell, human HepG2 whole cell, human A549 whole cell, rat heart tissue, mouse heart tissue. IHC: human breast carcinoma tissue, human lung cancer tissue, rat intestine tissue. ICC/IF: MCF-7 cell. Flow: 293T cell.

          靶标信息

          Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; desmoglein 2; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037

          查看更多 收起

          基因别名: AA408168; CDHF5; D18Ertd293e; DSG2; HDGC

          查看更多 收起

          UniProt ID: (Human) Q14126, (Mouse) O55111

          查看更多 收起

          Entrez Gene ID: (Human) 1829, (Mouse) 13511, (Rat) 307562

          查看更多 收起

          功能
          calcium ion binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication metal ion binding cadherin
          参与通路
          desmosome organization Purkinje myocyte development cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules response to progesterone maternal process involved in female pregnancy bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell action potential ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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