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Invitrogen
Diaveridine Recombinant Mouse Monoclonal Antibody (2C1)
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Diaveridine Antibody (MA566550) in SDS-PAGE
SDS-PAGE characterization of Diaveridine under reducing conditions. Lane M: Protein marker (kDa); Lane DVD: Purified Diaveridine Recombinant Monoclonal (Product # MA566550). Diaveridine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-392.
产品信息
MA566550
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2C1
抗原
Conjugate of DVD hapten and KLH.
偶联物
形式
Liquid
浓度
5.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Diaveridine is a dihydrofolate reductase inhibitor belonging to the 2,4-pyrimidinediamine class, primarily used as an antiprotozoal agent in combination with sulfaquinoxaline for the treatment and prophylaxis of coccidiosis and leucocytozoonosis in animals. It functions by inhibiting the enzyme dihydrofolate reductase, which is crucial for the synthesis of tetrahydrofolate, a cofactor necessary for the production of nucleic acids. Diaveridine is metabolized and eliminated in various animal tissues, including swine, chickens, and rats, with studies indicating its genotoxicity profile through various assays. Its structure allows it to act synergistically with other antibacterial agents, enhancing its efficacy in treating infections. The compound's toxicity has been assessed in acute and sub-chronic studies, providing a comprehensive understanding of its safety profile.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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