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Invitrogen
Dioxin Recombinant Mouse Monoclonal Antibody (1F9)
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Dioxin Antibody (MA566538) in SDS-PAGE
SDS-PAGE characterization of Dioxin under reducing conditions. Lane M: Protein marker (kDa); Lane DXN: Purified Dioxin Recombinant Monoclonal (Product # MA566538). Dioxin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-382.
产品信息
MA566538
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1F9
抗原
Conjugate of DXN hapten and KLH.
偶联物
形式
Liquid
浓度
5.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Dioxins, a group of chemically-related compounds known for their persistence and bioaccumulation, are primarily found as environmental pollutants. These compounds, including dioxin-like polychlorinated biphenyls (dl-PCBs), are lipophilic and accumulate in animal-origin foods, posing significant health risks due to their toxicological properties. Dioxins are produced through industrial processes, waste incineration, and open burning practices, leading to their widespread presence in the environment. Structurally, dioxins are characterized by their polychlorinated dibenzo-p-dioxin and polychlorinated dibenzofuran configurations, which contribute to their stability and resistance to degradation. Functionally, dioxins interfere with biological systems by binding to the aryl hydrocarbon receptor (AhR), disrupting endocrine functions and leading to various health issues, including cancer and immune system suppression. Recent advancements in detection methods, such as yeast-based bioreporters, have improved the sensitivity and cost-effectiveness of dioxin monitoring, aiding in environmental and food safety assessments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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