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Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Might be involved in the processing of visual information and/or visual learning. Important for Pavlovian conditioning: required in the mushroom body as a receptor conveying unconditional stimuli information, has a role in memory formation for aversive and appetitive learning. Sleep-deprivation-induced impairments in learning can be partially explained through alterations in dopamine signaling, Dop1R1 expression levels are reduced; sleep may have a role in restoring dopamine homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CG9652-PB; CG9652-PC; CG9652-PD; CG9652-PE; CG9652-PF; D-DOP1; D1 dopamine receptor; D1-like DA receptor; D1-Like dopamine receptor; D1-like receptor; D[[1]] dopamine receptor; DA D[[1]]-like receptor; dDA1; Dop1R1-PB; Dop1R1-PC; Dop1R1-PD; Dop1R1-PE; Dop1R1-PF; dopamine 1 receptor; Dopamine 1-like receptor 1; dopamine D1 receptor; dopamine D1-like receptor; dopamine receptor; Dopamine receptor 1; dopaminergic receptor; DopR; DopR1; DopR35EF; dumb; dumb DA receptor
基因别名: CG9652; D-Dop1; DA1; dDA1; dDA1/DmDOP1; DmDOP1; Dmel\CG9652; Dmel_CG9652; Dop1-R1; Dop1R; Dop1R1; DopR; DopR1; DopR35EF; DopR35F; DR1; DRD1; Dumb
UniProt ID: (Fruit fly) P41596
Entrez Gene ID: (Fruit fly) 41726
分子生物学功能: G-protein coupled receptor