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Invitrogen
Dopamine beta Hydroxylase Polyclonal Antibody
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Dopamine beta Hydroxylase Antibody (PA5-109618) in WB
Western blot analysis of Dopamine beta Hydroxylase in mouse brain. Samples were incubated with Dopamine beta Hydroxylase Polyclonal antibody (Product # PA5-109618) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.
产品信息
PA5-109618
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-200 of human DBH (NP_9588521)
偶联物
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MAKERGLISP SDFAQLQKYM EYSTKKVSDV LKLFEDGEMA KYVQGDAIGY EGFQQFLKIY LEVDNVPRHL SLALFQSFET GHCLNETNVT KDVVCLNDVS CYFSLLEGGR PEDKLEFTFK LYDTDRNGIL DSSEVDKIIL QMMRVAEYLD WDVSELRPIL QEMMKEIDYD GSGSVSQAEW VRAGATTVPL LVLLGLEMTL
靶标信息
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dopamine beta hydroxylase (dopamine beta-monooxygenase); Dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); Dopamine beta-monooxygenase; Dopamine-Beta-hydroxylase
基因别名: DBH; DBM; DOPBHY
UniProt ID: (Human) P09172, (Rat) Q05754, (Mouse) Q64237
Entrez Gene ID: (Human) 1621, (Rat) 25699, (Mouse) 13166
catalytic activity
dopamine beta-monooxygenase activity
copper ion binding
L-ascorbic acid binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
monooxygenase activity
oxidoreductase activity
metal ion binding
hydroxylase
oxidoreductase
metabolite interconversion enzyme
cytokine production
blood vessel remodeling
response to amphetamine
leukocyte mediated immunity
chemical synaptic transmission
memory
locomotory behavior
visual learning
regulation of cell proliferation
homoiothermy
dopamine catabolic process
norepinephrine biosynthetic process
catecholamine biosynthetic process
glucose homeostasis
fear response
maternal behavior
positive regulation of vasoconstriction
behavioral response to ethanol
response to pain
leukocyte migration
oxidation-reduction process
regulation of extrinsic apoptotic signaling pathway
catecholamine metabolic process
associative learning
response to iron ion
response to ozone
multicellular organism aging
response to organic cyclic compound
response to estradiol
social behavior
response to isolation stress
response to immobilization stress
response to drug
response to peptide hormone
response to ethanol
octopamine metabolic process
response to copper ion
sensory perception of taste
bone development
cellular response to manganese ion
cellular response to nicotine
