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Invitrogen
Doramectin Recombinant Mouse Monoclonal Antibody (1F5)
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Doramectin Antibody (MA566532) in SDS-PAGE
SDS-PAGE characterization of Doramectin under reducing conditions. Lane M: Protein marker (kDa); Lane DOR: Purified Doramectin Recombinant Monoclonal (Product # MA566532). Doramectin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-410.
产品信息
MA566532
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1F5
抗原
Conjugate of DOR hapten and KLH.
偶联物
形式
Liquid
浓度
2.3 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Doramectin is a 16-membered macrocyclic lactone used extensively in veterinary medicine for the treatment of parasitic infections in mammals. It is produced through the fermentation of Streptomyces avermitilis, a bacterium known for its ability to synthesize avermectins. Doramectin functions by binding to gamma-aminobutyric acid (GABA) receptors, which are crucial for its insecticidal activity. The structure of doramectin includes hydrogen bonds at the C4' position, enhancing its efficacy against parasites. It is available in injectable and pour-on formulations, primarily for cattle, and has been the subject of various studies aiming to improve its production and efficacy through genetic and chemical modifications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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