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Invitrogen
Dynactin 3 Polyclonal Antibody
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产品信息
PA5-19399
产品规格
种属反应
Human,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (QVALGNISSKRE) corresponding to the internal amino acids of DCTN3 (aa 41-52).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DCTN3; dynactin 3 (p22); Dynactin complex subunit 22 kDa subunit; dynactin light chain; Dynactin subunit 3; MGC111190; p22
基因别名: DCTN-22; DCTN22; DCTN3
UniProt ID: (Human) O75935
Entrez Gene ID: (Human) 11258, (Rat) 362504
