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Invitrogen
Dynein Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106973
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N terminal region of human DYNLL2 (aa 1-50).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 8 kDa dynein light chain; 8 kDa dynein light chain b; cytoplasmic dynein light polypeptide; cytosolic DH IC-1; DLC8b; DNCL1; dynein, cytoplasmic, light polypeptide 1; PIN; protein inhibitor of neuronal nitric oxide synthase; radial spoke 22 homolog; unnamed protein product
基因别名: DLC1; Dlc2; DLC8; DNCL1; DNCL1B; DNCLC1; hdlc1; LC8; LC8a; PIN; RSPH22
UniProt ID: (Human) P63167, (Human) Q96FJ2
Entrez Gene ID: (Human) 8655, (Human) 140735
microtubule-based process
spermatid development
substantia nigra development
positive regulation of intracellular transport
intraciliary retrograde transport
positive regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of phosphorylation
motile cilium assembly
positive regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of DNA strand resection involved in replication fork processing
cilium movement
sperm motility
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