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产品信息
PA5-89505
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_5424081)
偶联物
形式
Liquid
浓度
0.58 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805617
产品详细信息
Immunogen sequence: MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG; Positive Samples: A-549, A-431, Mouse brain, Mouse heart, Mouse kidney, Rat brain; Cellular Location: Cytoplasm, cytoskeleton
靶标信息
The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 8 kDa dynein light chain; 8 kDa dynein light chain b; 8kD LC; 8kDa LC; cytoplasmic dynein light polypeptide; cytosolic DH IC-1; DLC8; DLC8b; dynein LC8; Dynein light chain 1, cytoplasmic; Dynein light chain 2, cytoplasmic; Dynein light chain LC8-type 1; Dynein light chain LC8-type 2; dynein light chain-2; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; dynein, light chain, LC8-type 2; mPIN; PIN; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase; radial spoke 22 homolog
基因别名: 1700064A15Rik; 6720463E02Rik; 8kDLC; C87222; DLC1; DLC2; DLC8; DLC8b; DNCL1; DNCL1B; DNCLC1; DYNLL1; DYNLL2; HDLC1; LC8; LC8a; PIN; RSPH22
UniProt ID: (Human) P63167, (Human) Q96FJ2, (Rat) P63170, (Mouse) P63168, (Rat) Q78P75, (Mouse) Q9D0M5
Entrez Gene ID: (Human) 8655, (Human) 140735, (Rat) 58945, (Mouse) 56455, (Rat) 140734, (Mouse) 68097
G2/M transition of mitotic cell cycle
transcription, DNA-templated
regulation of transcription, DNA-templated
ER to Golgi vesicle-mediated transport
apoptotic process
female gamete generation
anatomical structure morphogenesis
viral process
macroautophagy
antigen processing and presentation of exogenous peptide antigen via MHC class II
substantia nigra development
actin cytoskeleton organization
intraciliary retrograde transport
negative regulation of phosphorylation
cilium morphogenesis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
microtubule-based process
synaptic target recognition
nitric oxide biosynthetic process
transport
neurotransmitter metabolic process
negative regulation of catalytic activity
regulation of catalytic activity
microtubule-based movement
negative regulation of nitric oxide biosynthetic process
metabolic process
intracellular transport
