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Invitrogen
E2F8 Polyclonal Antibody
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E2F8 Antibody (PA5-106867) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded E2F8 in rat lung tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with E2F8 polyclonal antibody (Product # PA5-106867) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106867
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human E2F8(Accession A0AVK6), corresponding to amino acid residues P788-C838.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total E2F8.
靶标信息
E2F transcription factors, such as E2F8, are essential for orchestrating expression of genes required for cell cycle progression and proliferation (Christensen et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2F 8; E2f family member 8; E2F-8; FLJ23311; Transcription factor E2F8
基因别名: 4432406C08Rik; AA410048; E2F-8; E2F8; RGD1308091
UniProt ID: (Mouse) Q58FA4
Entrez Gene ID: (Mouse) 108961, (Rat) 308607
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
identical protein binding
protein homodimerization activity
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell cycle
cell proliferation
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
cell cycle comprising mitosis without cytokinesis
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
