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Abnova
E4F1 Monoclonal Antibody (4B10)
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产品信息
H00001877-M03
产品规格
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4B10
抗原
E4F1 (NP_004415.2, 685 a.a. approximately 784 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: GHQIIVQNVT MDEETALGPE AAAADTITIA TPESLTEQVA MTLASAISEG TVLAARAGTS GTEQATVTMV SSEDIEILEH AGELVIASPE GQLEVQTVIV
靶标信息
May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.; FUNCTION: Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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