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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ECT2 Antibodies

          Invitrogen

          ECT2 Monoclonal Antibody (OTI2D9)

          高级验证
          查看其他11个ECT2抗体

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          Cite ECT2 Monoclonal Antibody (OTI2D9)

          • 抗体检测数据 (4)
          • 高级验证 (1)
          ECT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          ECT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 5

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          ECT2 Antibody (MA5-26870) in IHC (P)

          Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human ovary tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a ECT2 monoclonal antibody (Product # MA5-26870). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          ECT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ECT2 Antibody in Western Blot (WB)
          ECT2 Antibody in Western Blot (WB)
          ECT2 Antibody in Western Blot (WB)
          ECT2 Antibody
          ECT2 Monoclonal Antibody (OTI2D9)

          产品信息

          MA5-26870

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:2,000
          -

          免疫组化(石蜡) (IHC (P))

          1:150
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          OTI2D9

          抗原

          Human recombinant protein fragment corresponding to amino acids 175-438 of ECT2 produced in E.coli
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS, pH 7.3, with 1% BSA, 50% glycerol

          内含物

          0.02% sodium azide

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2723111

          靶标信息

          The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: epithelial cell transforming sequence 2 oncogene; Epithelial cell-transforming sequence 2 oncogene; FLJ10461; MGC138291; Protein ECT2

          查看更多 收起

          基因别名: ARHGEF31; ECT2

          查看更多 收起

          UniProt ID: (Human) Q9H8V3

          查看更多 收起

          Entrez Gene ID: (Human) 1894

          查看更多 收起

          功能
          signal transducer activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding Rho GTPase binding protein homodimerization activity G-protein modulator protein-binding activity modulator guanyl-nucleotide exchange factor
          参与通路
          cell morphogenesis cytokinesis protein transport activation of protein kinase activity positive regulation of cytokinesis regulation of Rho protein signal transduction intracellular signal transduction positive regulation of protein import into nucleus positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of GTPase activity positive regulation of neuron differentiation regulation of protein kinase activity regulation of small GTPase mediated signal transduction protein homooligomerization regulation of attachment of spindle microtubules to kinetochore cellular response to hydrogen peroxide bicellular tight junction assembly cellular response to calcium ion cellular response to ionizing radiation activation of GTPase activity
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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