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Invitrogen
EDEM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-120535
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 399-578 of human EDEM2 (NP_060687.2).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.96 mg/mL
规格
196 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: A375, HepG2.
Immunogen sequence: SIEKISKVEC GFATIKDLRD HKLDNRMESF FLAETVKYLY LLFDPTNFIH NNGSTFDAVI TPYGECILGA GGYIFNTEAH PIDPAALHCC QRLKEEQWEV EDLMREFYSL KRSRSKFQKN TVSSGPWEPP ARPGTLFSPE NHDQARERKP AKQKVPLLSC PSQPFTSKLA LLGQVFLDSS
靶标信息
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C20orf31; ER degradation enhancer, mannosidase alpha-like 2; ER degradation-enhancing alpha-mannosidase-like 2; ER degradation-enhancing-mannosidase-like protein 2; unnamed protein product
基因别名: 9530090G24Rik; bA4204.1; C20orf31; C20orf49
UniProt ID: (Human) Q9BV94, (Mouse) Q8BJT9
Entrez Gene ID: (Human) 55741, (Mouse) 108687
carbohydrate metabolic process
endoplasmic reticulum unfolded protein response
ERAD pathway
glycoprotein ERAD pathway
positive regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
glycoprotein metabolic process
viral protein processing
trimming of terminal mannose on C branch
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
