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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LLLDGLGCES CNVLAVEKYF LLLAEANSLV NAAVYSCRDA EMRRTFRRLL CCACLRQSTR ESVHYTSSAQ GGASTRIMLP ENGHPLMDST L
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: LPA receptor 2; LPA2 Receptor; Lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor Edg-4
基因别名: EDG4; LPA2; LPAR2
Entrez Gene ID: (Human) 9170