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EDS1/Enhanced disease susceptibility 1 Polyclonal Antibody
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EDS1/Enhanced disease susceptibility 1 Antibody (AS13-2751) in WB
Samples: 1 -40 µg of Arabidopsis thaliana whole leaf extract, non treated 2 -40 µg of Arabidopsis thaliana whole leaf extract, treated with Pst Avr B 3 h 3- 40 µg of Arabidopsis thaliana whole leaf extract, old-6 weeks 4-40 µg of Solanum lycopersicum (negative control) 8 discs extract, control leaf 5-40 µg of Solanum lycopersicum (negative control) 8 discs extract, wounded leaf 6-40 µg of Arabidopsis thalia... View More
产品信息
AS13-2751
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana EDS1 sequence.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
EDS1 encodes an intracellular, predominantly nucleocytoplasmic protein that can accumulate in the nucleus during immune activation, consistent with a role in transcriptional defense reinforcement. The protein is composed of an N-terminal lipase-like alpha/beta-hydrolase fold (class 3 lipase-like domain) that resembles catalytic lipases but is generally described as non-catalytic in immune signaling contexts, coupled to a C-terminal region that is essential for activity and contributes to formation of higher-order signaling-competent complexes. Functionally, EDS1 is a central regulatory node in plant innate immunity, required for robust basal resistance to biotrophic and hemi-biotrophic pathogens and for effector-triggered immunity mediated by Toll/interleukin1 receptor-type NLR receptors. EDS1 acts through obligate, molecularly distinct heterodimers with PAD4 or SAG101 that occupy different intracellular pools and provide nonredundant signaling outputs, collectively promoting salicylic acid-associated defense programs, pathogen-restricting responses, and appropriate cell-death-associated immunity when triggered by intracellular immune receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATEDS1; EDS1 PROTEIN; enhanced disease susceptibility 1
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