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Rockland
EFCAB4A Polyclonal Antibody
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产品信息
600-401-AZ2
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-EFCAB4A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human EFCAB4A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; Calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A
基因别名: 6330520A15Rik; BC026645; Cracr2a; CRACR2B; Efcab4; EFCAB4A; RGD1560911
UniProt ID: (Human) Q8N4Y2, (Mouse) Q80ZJ8, (Rat) B0BNK9
Entrez Gene ID: (Human) 283229, (Mouse) 213573, (Rat) 309112
