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Abnova
EFCAB4A Monoclonal Antibody (2F10)
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产品信息
H00283229-M06
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2F10
抗原
EFCAB4A (NP_775855.2, 1 a.a. approximately 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MASPGKPGAD EAQEEEGELE GGSAGPRAAI LEQAEELFLL CDKEAKGFIT KHDLQGLQSD LPLTPEQLEA VFESLDQAHT GFLTAREFCL GLGMFVGVAS AQGANPCRTP EETFESGGLD VQGTAGSLDE EEEEEERFHT VLEQLGVAPV LGEQRAVRTL WARLQRERPE LLGSFEDVLI RASACLEEAA RERDGLEQAL RRRESEHERE VRALYEETEQ LREQSRRPPS QNFARGERRS RLELELQIRE QDLERAGLRQ RERRGRRLQE HAERESQPAT ATGAAQGAEY TAAG
靶标信息
EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; Calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A
基因别名: CRACR2B; EFCAB4A
UniProt ID: (Human) Q8N4Y2
Entrez Gene ID: (Human) 283229
