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Invitrogen
EFHC2 Polyclonal Antibody
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产品信息
PA5-56951
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KEKFHKSQHW GFCNNVMMLV SDEKPGIGGE PLLGQKIKPK CSIYPKGDGS DVPSWVAFDK QVLSFDAYLE EEVLDKSQTN YRIR
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.
靶标信息
EFHC2 (EF-hand domain-containing protein 2) is a gene located on the X chromosome at position Xp11.4. The protein encoded by EFHC2 is characterized by the presence of EF-hand motifs, which are helix-loop-helix structural domains capable of binding calcium ions. The EFHC2 protein is involved in various cellular processes, particularly those that are calcium-dependent, such as signal transduction and regulation of enzyme activities. EFHC2 has been implicated in neurological functions and conditions. For instance, it has been studied in the context of epilepsy, where variants in the gene are associated with increased susceptibility to juvenile myoclonic epilepsy. Additionally, EFHC2 is expressed in the brain and testis, suggesting roles in neurodevelopment and reproduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EF-hand domain (C-terminal) containing 2; EF-hand domain-containing family member C2; mental retardation, X-linked 74
基因别名: 4933407D04Rik; dJ1158H2.1; EFHC2; mRib72-2; MRX74
UniProt ID: (Human) Q5JST6, (Mouse) Q9D485
Entrez Gene ID: (Human) 80258, (Mouse) 74405
