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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SDLIRSMEQL TSSLNEGENT HMIHQKTQEK IWEFKGKLEQ HLTGRRWRNI VDQIWSFGPR KCGPNILVNK SEDFQNSVWT GPADKASKEA SRYRDLGNSI VSGFQLATL
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Elongation factor Tu GTP-binding domain-containing protein 1; Elongation factor-like 1; Elongation factor-like GTPase 1; Protein FAM42A
基因别名: EFL1; EFTUD1; FAM42A
Entrez Gene ID: (Human) 79631