Search Thermo Fisher Scientific
图: 1 / 4
Positive Samples: 293T, HeLa, HepG2, MCF7, C2C12, Mouse brain, Rat brain
Immunogen sequence: MSASQDSRSR DNGPDGMEPE GVIESNWNEI VDSFDDMNLS ESLLRGIYAY GFEKPSAIQQ RAILPCIKGY DVIAQAQSGT GKTATFAISI LQQIELDLKA
The eIF4A proteins are involved in many aspects of RNA metabolism due to their RNA-binding capacity and ATPase activity. eIF4A1 and eIF4A2 are cytoplasmic, whereas eIF4A3 is nuclear-localized. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-1; ATP-dependent RNA helicase eIF4A-2; ATP-dependent RNA helicase eIF4A-3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; DEAD box protein 48; eIF-4A-I; eIF-4A-II; eIF-4A-III; eIF4A-I; eIF4A-II; eIF4A-III; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4A-II; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-like NUK-34; eukaryotic initiation factor 4AI; Eukaryotic translation initiation factor 4A isoform 3; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A, isoform 2; eukaryotic translation initiation factor 4A, isoform 3; hNMP 265; initiation factor eIF-4A long form; NMP 265; Nuclear matrix protein 265; protein synthesis initiation factor 4AII
基因别名: 2400003O03Rik; 4833432N07Rik; BM-010; DDX2A; DDX2B; DDX48; EIF-4A; eIF-4A-I; eIF-4A-II; Eif4; EIF4A; eIF4A-I; eIF4A-II; eIF4A-III; EIF4A1; EIF4A2; EIF4A3; eIF4AIII; EIF4F; KIAA0111; mKIAA0111; MUK34; NMP265; NUK34; RCPS
UniProt ID: (Human) P60842, (Human) Q14240, (Human) P38919, (Mouse) P60843, (Mouse) P10630, (Rat) Q5RKI1, (Mouse) Q91VC3, (Rat) Q3B8Q2
Entrez Gene ID: (Human) 1973, (Human) 1974, (Human) 9775, (Mouse) 13681, (Rat) 287436, (Mouse) 13682, (Rat) 303831, (Mouse) 192170, (Rat) 688288