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Invitrogen
EKLF Polyclonal Antibody
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图: 1 / 3
EKLF Antibody (PA5-86441) in WB
Western blot analysis of EKLF in Lane 1: C6 whole cell lysate (40 µg), Lane 2: SP2/0 whole cell lysate (40 µg), Lane 3: MCF-7 whole cell lysate (40 µg), Lane 4: K562 whole cell lysate (40 µg). Sample was incubated with EKLF polyclonal antibody (Product # PA5-86441) using a 1:500 dilution.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-86441
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, corresponding to amino acids 288-335 of Human EKLF.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
KLF1 is a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant Inblood phenotype.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EKLF; Erythroid krueppel-like transcription factor; erythroid Kruppel-like factor; erythroid transcription factor; Krueppel-like factor 1; neonatal anemia
基因别名: EKLF; KLF1; Nan
Entrez Gene ID: (Rat) 304666, (Mouse) 16596
in utero embryonic development
liver development
chromatin remodeling
erythrocyte differentiation
embryonic hemopoiesis
erythrocyte maturation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
erythrocyte development
cellular response to peptide
transcription, DNA-templated
regulation of transcription, DNA-templated
Disclaimer
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