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Invitrogen
ELOA Polyclonal Antibody
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FIGURE: 1 / 3
ELOA Antibody (PA5-115175) in ICC/IF
Immunocytochemistry analysis of ELOA in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115175). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115175
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ELOA(Accession Q14241), corresponding to amino acid residues E135-H185.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Elongin A1.
Target Information
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EloA; EloA2; Elongin 110 kDa subunit; Elongin A; Elongin A2; Elongin-A; Elongin-A2; RNA polymerase II transcription factor SIII subunit A1; RNA polymerase II transcription factor SIII subunit A2; SIII p110; TCEB3B; TCEB3L; transcription elongation factor (SIII) elongin A2 elongin A2; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3; Transcription elongation factor B polypeptide 3B
Gene Aliases: 110kDa; AA408125; ELOA; ELOA2; HsT832; MSTP059; SIII; SIII p110; TCEB3; TCEB3A; TCEB3B; TCEB3L
UniProt ID: (Human) Q14241, (Human) Q8IYF1, (Mouse) Q8CB77
Entrez Gene ID: (Human) 6924, (Human) 51224, (Mouse) 27224
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
transcription from RNA polymerase II promoter
regulation of DNA-templated transcription, elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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