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Rockland
ELOVL7 Polyclonal Antibody
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FIGURE: 1 / 3
ELOVL7 Antibody (600-401-AZ8) in ICC/IF
Immunofluorescence Microscopy of ELOVL7 antibody. Tissue: Human liver tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: ELOVL7 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: ELOVL7 is a membrane protein. Staining: ELOVL7 as red fluorescent signal.
Product Details
600-401-AZ8
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-ELOVL7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human ELOVL7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-keto acyl-CoA synthase ELOVL7; Elongation of very long chain fatty acids protein 7; elongation of very long chain fatty acids-like 7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; ELOVL fatty acid elongase 7; Very long chain 3-ketoacyl-CoA synthase 7; Very long chain 3-oxoacyl-CoA synthase 7; Very long chain fatty acid elongase 7; very-long-chain 3-oxoacyl-CoA synthase 7
Gene Aliases: 9130013K24Rik; AI840082; ELOVL7
UniProt ID: (Human) A1L3X0, (Mouse) Q9D2Y9
Entrez Gene ID: (Human) 79993, (Mouse) 74559
unsaturated fatty acid biosynthetic process
fatty acid elongation, saturated fatty acid
sphingolipid biosynthetic process
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
long-chain fatty-acyl-CoA biosynthetic process
very long-chain fatty acid biosynthetic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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