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Invitrogen
EMAP II Polyclonal Antibody, PeproTech®
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EMAP II Antibody (500-P172G-1MG) in WB
Western Blot: To detect Human EMAP-II by Western Blot analysis EMAP II Polyclonal Antibody (Product # 500-P172G-1MG) can be used at a concentration of 0.1- 0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human EMAP-II is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P172G-1MG
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Goat
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human EMAP-II
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
AA Sequence of recombinant protein: discontinued.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human EMAP-II. Anti-Human EMAP-II-specific antibody was purified by affinity chromatography employing an immobilized Human EMAP-II matrix.
Sandwich ELISA: To detect Human EMAP-II by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human EMAP-II (500-P172GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human EMAP-II.
Western Blot: To detect Human EMAP-II by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human EMAP-II is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
靶标信息
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; ARS-interacting multifunctional protein 1; endothelial monocyte-activating polypeptide 2; endothelial-monocyte activating polypeptide II; mca1; Multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
基因别名: AIMP1; EMAP2; EMAPII; HLD3; p43; SCYE1
UniProt ID: (Human) Q12904
Entrez Gene ID: (Human) 9255
angiogenesis
negative regulation of endothelial cell proliferation
glucose metabolic process
tRNA aminoacylation for protein translation
apoptotic process
chemotaxis
inflammatory response
cell adhesion
signal transduction
cell-cell signaling
response to wounding
leukocyte migration
defense response to virus
