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Recommended positive controls: NT2D1.
Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (92%), Rhesus Monkey (99%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BTB/POZ KELCH domain protein; Ectoderm-neural cortex protein 2; ectoderm-neural cortex-1; ectodermal-neural cortex 2; ENC-2; FLJ12587; FLJ45015; kelch-like 25; kelch-like family member 25; Kelch-like protein 25
基因别名: 2810402K13Rik; BC027373; Enc-1; ENC-2; ENC2; KLHL25; RGD1310815
UniProt ID: (Human) Q9H0H3, (Rat) Q4KLM4, (Mouse) Q8R2P1
Entrez Gene ID: (Human) 64410, (Rat) 293023, (Mouse) 207952