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Abnova
ENDOG Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00002021-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ENDOG (AAH04922.1, 50 a.a. approximately 297 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: ELPPVPGGPR GPGELAKYGL PGLAQLKSRE SYVLCYDPRT RGALWVVEQL RPERLRGDGD RRECDFREDD SVHAYHRATN ADYRGSGFDR GHLAAAANHR WSQKAMDDTF YLSNVAPQVP HLNQNAWNNL EKYSRSLTRS YQNVYVCTGP LFLPRTEADG KSYVKYQVIG KNHVAVPTHF FKVLILEAAG GQIELRTYVM PNAPVDEAIP LERFLVPIES IERASGLLFV PNILARAGSL KAITAGSK
靶标信息
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
DNA catabolic process
apoptotic DNA fragmentation
DNA recombination
cellular response to DNA damage stimulus
response to mechanical stimulus
positive regulation of autophagy
negative regulation of TOR signaling
mitochondrial DNA catabolic process
response to estradiol
cellular response to oxidative stress
cellular response to calcium ion
cellular response to glucose stimulus
cellular response to hypoxia
positive regulation of mitochondrial DNA replication
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of apoptotic DNA fragmentation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
