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Invitrogen
ENY2 Polyclonal Antibody
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Product Details
PA5-115182
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ENY2(Accession Q9NPA8), corresponding to amino acid residues H49-A99.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ENY2.
Target Information
ENY2 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: e(y)2 homolog; e(y)2 protein; enhancer of yellow 2 homolog; Enhancer of yellow 2 transcription factor homolog; enhancer of yellow eye homolog; ENY 2; ENY-2; ENY2; Transcription and mRNA export factor ENY2
Gene Aliases: 1810057B09Rik; 6720481I12; DC6; e(y)2; ENY2; Ey2; Sus1
UniProt ID: (Human) Q9NPA8, (Mouse) Q9JIX0
Entrez Gene ID: (Human) 56943, (Rat) 685258, (Mouse) 223527
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein transport
histone deubiquitination
poly(A)+ mRNA export from nucleus
positive regulation of transcription, DNA-templated
negative regulation of insulin secretion involved in cellular response to glucose stimulus
mRNA export from nucleus
transcription, DNA-templated
regulation of transcription, DNA-templated
transport
chromatin modification
mRNA transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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