Invitrogen

EOMES Monoclonal Antibody (WD1928), eBioscience™

Name: EOMES Monoclonal Antibody (WD1928), eBioscience\u2122
Brand: Invitrogen
SKU: 14-4877-82

18个已发表图片

39 篇参考文献

查看其他34个EOMES抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)
已发表图片 (18)

EOMES Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 20

EOMES Antibody (14-4877-82) in IHC (P)

Immunohistochemistry of formalin-fixed paraffin embedded human thymus using 5 µg/mL Mouse IgG1 K Isotype Control Purified (left) or 5 µg/mL Anti-Human EOMES Purified (right) followed by Anti-Mouse IgG Biotin, Avidin HRP, and DAB visualization. Nuclei are counterstained with hematoxylin.

EOMES Antibody in Immunohistochemistry (IHC)

Product Image Gallery

产品信息

14-4877-82

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫组化 (IHC)

查看4篇已发表文章 4篇已发表文章

免疫组化（石蜡） (IHC (P))

5 µg/mL

免疫细胞化学 (ICC/IF)

查看3篇已发表文章 3篇已发表文章

流式细胞分析 (Flow)

查看28篇已发表文章 28篇已发表文章

功能检测 (Functional)

查看1篇已发表文章 1篇已发表文章

亲和纯化 (AP)

查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Pig

已发表种属

C. elegans, Human, Mouse

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

WD1928

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.09% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2572882

产品详细信息

Description: This WD1928 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2). Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates. In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells. Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R.

Applications Reported: This WD1928 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.

Applications Tested: This WD1928 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low or high pH antigen retrieval and can be used at less than or equal to 5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Purity: Greater than 90%, as determined by SDS-PAGE.

Aggregation: Less than 10%, as determined by HPLC.

Filtration: 0.2 µm post-manufacturing filtered.

靶标信息

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

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