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Invitrogen
EOMES Recombinant Mouse Monoclonal Antibody (WD1928)
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EOMES Antibody (740127M) in WB
Western blot was performed using EOMES Recombinant Mouse Monoclonal Antibody (WD1928) (Product # 740127M) and ~75, 80 kDa bands corresponding to EOMES was observed in NK-92 as compared to HeLa and THP-1 which is reported to be negative for EOMES expression. Nuclear-enriched extracts (1% SDS) (30 µg lysate) of NK-92 (Lane 1), HeLa (Lane 2) and THP-1 (Lane 3) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot™... View More
产品信息
740127M
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
WD1928
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Recombinant mouse monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
靶标信息
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Eomesodermin homolog; T-box brain protein 2; T-brain-2; unnamed protein product
基因别名: EOMES; TBR2
UniProt ID: (Human) O95936
Entrez Gene ID: (Human) 8320
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
chromatin DNA binding
sequence-specific DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
endoderm formation
mesoderm formation
endodermal cell fate specification
neuron migration
blastocyst development
trophectodermal cell differentiation
adaptive immune response
CD8-positive, alpha-beta T cell differentiation involved in immune response
immune system process
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
gastrulation
brain development
endoderm development
anatomical structure morphogenesis
cardioblast differentiation
gene expression
regulation of gene expression
stem cell population maintenance
olfactory bulb development
cerebral cortex regionalization
cerebral cortex neuron differentiation
cerebral cortex development
neurogenesis
cell differentiation
neuron differentiation
skeletal muscle cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mesendoderm development
astrocyte differentiation
cell differentiation involved in embryonic placenta development
mesodermal to mesenchymal transition involved in gastrulation
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