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Fabgennix
EPAC2 Polyclonal Antibody, FITC
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产品信息
EPAC2-FITC
应用
建议稀释比
已发表文章
产品规格
种属反应
Horse,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein.Sequence:CPREQFDSLTPLPEQEGPT
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP-dependent Rap1 guanine-nucleotide exchange factor; cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; cAMP-regulated guanine nucleotide exchange factor IIB; EPAC 2; Exchange factor directly activated by cAMP 2; Exchange protein directly activated by cAMP 2; gefii; putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; Rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4
基因别名: 1300003D15Rik; 5730402K07Rik; 6330581N18Rik; CAMP-GEFII; CAMPS; CGEF2; EPAC; EPAC 2; Epac-2; EPAC2; mKIAA4040; Nbla00496; RAPGEF4
UniProt ID: (Human) Q8WZA2, (Mouse) Q9EQZ6
Entrez Gene ID: (Human) 11069, (Horse) 100064121, (Rat) 252857, (Mouse) 56508
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
calcium ion regulated exocytosis
regulation of exocytosis
cAMP-mediated signaling
insulin secretion
positive regulation of GTPase activity
regulation of insulin secretion
exocytosis
signal transduction
heart development
positive regulation of smooth muscle cell migration
regulation of protein kinase activity
regulation of dendrite development
negative regulation of synaptic transmission
regulation of protein phosphorylation
intracellular signal transduction
positive regulation of action potential
positive regulation of protein secretion
