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Invitrogen
EPB41 Polyclonal Antibody
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EPB41 Antibody (PA5-102613) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-EPB41 (Tyr418, Tyr660) in human kidney tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-EPB41 (Tyr418, Tyr660) polyclonal antibody (Product # PA5-102613) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-102613
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EPB41(Accession P11171), corresponding to amino acid residues H681-L731.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total EPB41.
靶标信息
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4.1R; Band 4.1; elliptocytosis 1, RH-linked; EPB4.1; Erythrocyte membrane protein band 4.1; erythrocyte protein band 4.1; erythrocyte surface protein band 4.1; P4.1; Protein 4.1; Protein 4.1R
基因别名: 4.1R; AI415518; D4Ertd442e; E41P; EL1; Elp-1; Elp1; Epb4.1; EPB41; HE; Kiaa4056; mKIAA4056; RGD1564762
UniProt ID: (Human) P11171, (Mouse) P48193
Entrez Gene ID: (Human) 2035, (Mouse) 269587, (Rat) 313052
