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Invitrogen
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Antibody detects endogenous levels of total EPS15L1.
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epidermal growth factor receptor pathway substrate 15-like 1; Epidermal growth factor receptor pathway substrate 15-related sequence; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15-related protein; Eps15-rs; Eps15R
基因别名: 9830147J04Rik; AI593686; Eps15-rs; EPS15L1; EPS15R
UniProt ID: (Human) Q9UBC2, (Mouse) Q60902
Entrez Gene ID: (Human) 58513, (Mouse) 13859, (Rat) 361120