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Invitrogen
EPS15R Polyclonal Antibody
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EPS15R Antibody (PA5-109690) in WB
Western blot analysis of EPS15R in extracts of various cell lines. Samples were incubated with EPS15R Polyclonal antibody (Product # PA5-109690) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-109690
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1).
偶联物
形式
Liquid
浓度
3.02 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QMISSLKTQI QSQESDLKSQ EDDLNRAKSE LNRLQQEETQ LEQSIQAGRV QLETIIKSLK STQDEINQAR SKLSQLHESR QEAHRSLEQY DQVLDGAHGA SLTDLANLSE GVSLAERGSF GAMDDPFKNK ALLFSNNTQE LHPDPFQTED PFKSDPFKGA DPFKGDPFQN DPFAEQQTTS TDPFGGDPFK ESDPFRGSAT DDFFKKQTKN DPFTSDPFTK NPSLPSKLDP FESSDPFSSS SVSSKGSDPF GTLDPFGSGS FNSAEGFADF SQMSKVKVHL
靶标信息
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epidermal growth factor receptor pathway substrate 15-like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15-related protein; Eps15R
基因别名: EPS15L1; EPS15R
UniProt ID: (Human) Q9UBC2
Entrez Gene ID: (Human) 58513
