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Immunogen sequence: EIALEQKKEE CLKMESQLKK AHEAALEARA SPEMSDRIQH LEREITRYKD ESSKAQAEVD RLLEILKEVE NEKNDKDKKI AELERQVKDQ NKKVANLKHK EQVEKKKSAQ MLEEARRRED NLNDSSQQLQ DSLRKKDDRI EELEEALRES V; Positive Samples: HepG2, Jurkat, NIH/3T3, Rat brain; Cellular Location: Cytoplasm, Golgi apparatus membrane, Membrane, Peripheral membrane protein
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAST2; CAZ-associated structural protein 2; ELKS/Rab6-interacting/CAST family member 1; ERC protein 1; ERC-1; FLJ31750; MGC12974; OTTHUMP00000160633; RAB6 interacting protein 2; RAB6-interacting protein 2; RIM-Binding Protein
基因别名: 4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST; CAST2; ELKS; ERC; ERC-1; ERC1; ERC1b; KIAA1081; mKIAA1081; RAB6IP2; RAB6IP2A; RAB6IP2B
UniProt ID: (Human) Q8IUD2, (Mouse) Q99MI1
Entrez Gene ID: (Human) 23085, (Rat) 266806, (Mouse) 111173