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Invitrogen
ERCC6L Polyclonal Antibody
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产品信息
PA5-50405
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to residues near the C terminal of human excision repair cross-complementation group 6-like
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total ERCC6L protein.
靶标信息
ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-dependent helicase ERCC6-like; DNA excision repair protein ERCC-6-like; excision repair cross-complementation group 6 like; excision repair cross-complementation group 6-like; excision repair cross-complementing rodent repair deficiency complementation group 6 - like; excision repair cross-complementing rodent repair deficiency, complementation group 6-like; excision repair protein ERCC6-like; FLJ20105; MGC131695; PLK1-interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ-HCC-15
基因别名: ERCC6L; PICH; RAD26L
UniProt ID: (Human) Q2NKX8
Entrez Gene ID: (Human) 54821
