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Invitrogen
ERMAP Polyclonal Antibody
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产品信息
PA5-60029
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PLVICSELHK SEESIVPRPE GKGHANGDVS LKVNSSLLPP KAPELKDIIL SLPPDLGPAL QELKAPS
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 64%.
靶标信息
Erythroblast membrane-associated protein (ERMAP) is a gene situated on chromosome 1p34.2, encoding a protein primarily associated with erythroblast cells. ERMAP is expressed in erythroid lineage cells and plays a crucial role as an adhesion molecule, involved in the maturation and stability of the erythrocyte membrane. This protein is associated with the Scianna blood group system, and variations within the ERMAP gene lead to different antigenic expressions which are important in transfusion medicine. ERMAP is also significant in mediating cell-cell adhesion processes essential for erythropoiesis, where it facilitates receptor-ligand interactions in hematopoietic stem cells. Mutations or polymorphisms in ERMAP can result in altered blood group antigens, impacting blood transfusion compatibility and potentially leading to hemolytic reactions. Given its distinct role in erythrocyte formation, ERMAP is a subject of interest for further research into blood-related disorders and their genetic underpinnings.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: erythroblast membrane-associated protein (Scianna blood group); Erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; Radin blood group; Radin blood group (Rd); Radin blood group antigen; RDMGC118812; Scianna blood group; Scianna blood group (Sc); Scianna blood group antigen; SCMGC118813
基因别名: BTN5; ERMAP; PRO2801; RD; SC
UniProt ID: (Human) Q96PL5
Entrez Gene ID: (Human) 114625
