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Invitrogen
ETV3 Polyclonal Antibody
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产品信息
PA5-52107
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EKEEHTQEEG TVPSRTIEEE KGTIFARPAA PPIWPSVPIS TPSGEPLEVT EDSEDRPGKE PSAPEKKEDA LMPPKLRLKR RWNDDPEARE LSKSGKFLWN G
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 79%.
靶标信息
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: ETS domain transcriptional repressor PE1; ETS translocation variant 3; ets variant gene 3, ETS family transcriptional repressor; Mitogenic Ets transcriptional suppressor; PE-1
基因别名: bA110J1.4; ETV3; METS; PE-1; PE1
UniProt ID: (Human) P41162
Entrez Gene ID: (Human) 2117
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
molecular_function
DEAD/H-box RNA helicase binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
biological_process
negative regulation of cell proliferation
cell differentiation
cellular response to granulocyte macrophage colony-stimulating factor stimulus
