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Abnova
ETV5 Monoclonal Antibody (7C10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00002119-M02
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
7C10
抗原
ETV5 (NP_004445, 181 a.a. approximately 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: LPEPGPQQQT FAVPRPPHQP LQMPKMMPEN QYPSEQRFQR QLSEPCHPFP PQPGVPGDNR PSYHRQMSEP IVPAAPPPPQ GFKQEYHDPL YEHGVPGMPG PPAHGFQSPM
靶标信息
ETS variant 5, transcription factor of the ETS family, divergent member of the winged helix-turn-helix superfamily, expressed in brain, placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ETS translocation variant 5; ets variant gene 5; ets variant gene 5 (ets-related molecule); Ets-related protein ERM
基因别名: 1110005E01Rik; 8430401F14Rik; ERM; ETV5
UniProt ID: (Mouse) Q9CXC9
Entrez Gene ID: (Rat) 303828, (Mouse) 104156
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
molecular_function
transcription factor activity, sequence-specific DNA binding
transcription regulatory region DNA binding
DNA binding
sequence-specific DNA binding
winged helix/forkhead transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
neuromuscular synaptic transmission
locomotory behavior
cellular response to oxidative stress
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
male germ-line stem cell asymmetric division
regulation of synapse organization
positive regulation of glial cell proliferation
regulation of branching involved in mammary gland duct morphogenesis
skeletal muscle acetylcholine-gated channel clustering
regulation of transcription, DNA-templated
cell differentiation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
