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Invitrogen
EYA1 Polyclonal Antibody
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EYA1 Antibody (PA5-117158) in IHC (P)
Immunohistochemistry analysis of EYA1 in paraffin-embedded human placenta. Samples were incubated with EYA1 Polyclonal antibody (Product # PA5-117158) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-117158
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.85 mg/mL
规格
185 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: SH-SY5Y, 293T, Mouse testis, Mouse brain, Rat brain
Immunogen sequence: NSLTNSSGFN SSQQDYPSYP SFGQGQYAQY YNSSPYPAHY MTSSNTSPTT PSTNATYQLQ EPPSGITSQA VTDPTAEYST IHSPSTPIKD SDSDRLRRGS D
靶标信息
This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EYA transcriptional coactivator and phosphatase 1; Eyes absent; eyes absent 1 homolog; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053; Protein phosphatase EYA1
基因别名: bor; EYA1
UniProt ID: (Mouse) P97767
Entrez Gene ID: (Mouse) 14048, (Rat) 502935
establishment of mitotic spindle orientation
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
outflow tract morphogenesis
DNA repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein dephosphorylation
cellular response to DNA damage stimulus
multicellular organism development
pattern specification process
mesodermal cell fate specification
organ morphogenesis
response to ionizing radiation
striated muscle tissue development
chromatin modification
histone dephosphorylation
protein sumoylation
cellular protein localization
establishment or maintenance of apical/basal cell polarity
peptidyl-tyrosine dephosphorylation
aorta morphogenesis
ear morphogenesis
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
cell fate commitment
regulation of neuron differentiation
positive regulation of DNA repair
positive regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
neuron fate specification
embryonic skeletal system morphogenesis
semicircular canal morphogenesis
anatomical structure development
positive regulation of epithelial cell proliferation
pharyngeal system development
lung epithelial cell differentiation
otic vesicle development
otic vesicle morphogenesis
positive regulation of secondary heart field cardioblast proliferation
cochlea morphogenesis
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
biological_process
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