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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Endothelin 3 Antibodies

          Invitrogen

          Endothelin 3 Monoclonal Antibody (3B6)

          查看其他9个Endothelin 3抗体

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          Cite Endothelin 3 Monoclonal Antibody (3B6)

          • 抗体检测数据 (1)
          Endothelin 3 Antibody in Immunocytochemistry (ICC/IF)
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          Endothelin 3 Antibody in Immunocytochemistry (ICC/IF)
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          图: 1 / 1

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          Endothelin 3 Antibody (MA5-61573) in ICC/IF

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          Endothelin 3 Antibody in Immunocytochemistry (ICC/IF)

          产品信息

          MA5-61573

          应用
          建议稀释比
          已发表文章

          免疫细胞化学 (ICC/IF)

          8-25 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          3B6

          抗原

          Human Endothelin-3 synthetic peptide

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Lyophilized

          浓度

          0.5 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS with trehalose

          内含物

          no preservative

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3702185

          产品详细信息

          Reconstitute at 0.5 mg/mL in sterile PBS.

          靶标信息

          The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: Endothelin-3; ET 3; ET-3; MGC15067; MGC61498; PPET3; Preproendothelin 3; Preproendothelin-3; RP4-614C15.1

          查看更多 收起

          基因别名: EDN3; ET-3; ET3; HSCR4; PPET3; WS4B

          查看更多 收起

          UniProt ID: (Human) P14138

          查看更多 收起

          Entrez Gene ID: (Human) 1908

          查看更多 收起

          功能
          receptor binding hormone activity endothelin B receptor binding peptide hormone
          参与通路
          neural crest cell migration positive regulation of leukocyte chemotaxis regulation of systemic arterial blood pressure by endothelin cellular calcium ion homeostasis signal transduction cell surface receptor signaling pathway cell-cell signaling multicellular organism development blood circulation positive regulation of cell proliferation positive regulation of heart rate regulation of gene expression cellular magnesium ion homeostasis artery smooth muscle contraction vein smooth muscle contraction regulation of vasoconstriction peptide hormone secretion neuron differentiation melanocyte differentiation neutrophil chemotaxis vasoconstriction positive regulation of MAP kinase activity positive regulation of cell differentiation positive regulation of mitotic nuclear division positive regulation of hormone secretion inositol phosphate-mediated signaling regulation of developmental pigmentation positive regulation of potassium ion transmembrane transport
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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