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Invitrogen
Enramycin Recombinant Mouse Monoclonal Antibody (1A3)
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Enramycin Antibody (MA566530) in SDS-PAGE
SDS-PAGE characterization of Enramycin under reducing conditions. Lane M: Protein marker (kDa); Lane ERM: Purified Enramycin Recombinant Monoclonal (Product # MA566530). Enramycin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-449.
产品信息
MA566530
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1A3
抗原
Conjugate of ERM hapten and KLH.
偶联物
形式
Liquid
浓度
1.4 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Enramycin, also known as enduracidin, is a polypeptide antibiotic primarily used as a safe animal feed additive. It is produced by the bacterium Streptomyces fungicidicus and exhibits potent antimicrobial activities against Gram-positive bacteria. Enramycin functions by inhibiting bacterial cell wall synthesis, specifically targeting the lipid II precursor, which is crucial for peptidoglycan biosynthesis. Structurally, enramycin is composed of cyclic peptide chains that contribute to its stability and efficacy. The gene responsible for enramycin production is located within the Streptomyces genome, and its biosynthesis involves complex enzymatic pathways. Enramycin's purification process involves macroporous resin adsorption and reversed phase chromatography, ensuring high purity for its application in animal feeds. Despite its effectiveness, the emergence of antimicrobial resistance poses challenges to its long-term utility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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