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Invitrogen
Enterotoxin C Recombinant Mouse Monoclonal Antibody (4B3)
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Enterotoxin C Antibody (MA566525) in SDS-PAGE
SDS-PAGE characterization of Enterotoxin C under reducing conditions. Lane M: Protein marker (kDa); Lane ETC-D: Purified Enterotoxin C Recombinant Monoclonal (Product # MA566525). Enterotoxin C showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-313.
产品信息
MA566525
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4B3
抗原
Enterotoxin C.
偶联物
形式
Liquid
浓度
6.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Enterotoxin C, specifically staphylococcal enterotoxin C (SEC), is a protein toxin produced by Staphylococcus aureus, known for causing foodborne illnesses such as staphylococcal food poisoning. The gene encoding SEC, known as sec, is located on the bacterial chromosome and spans 801 base pairs, encoding a protein of 266 amino acids, including a 27 amino acid signal peptide. Upon cleavage of the signal peptide, the mature protein consists of 239 amino acids. SEC is part of a superfamily of staphylococcal enterotoxins, which exhibit potent superantigenic activity, disrupting adaptive immunity and leading to symptoms such as diarrhea and vomiting. The structural diversity of SEC variants contributes to its virulence and ability to cause a wide range of diseases. SEC's mechanism of action involves binding to major histocompatibility complex molecules and T-cell receptors, leading to massive cytokine release and immune system activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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