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Invitrogen
Enterotoxin E Recombinant Mouse Monoclonal Antibody (8F3)
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Enterotoxin E Antibody (MA566520) in SDS-PAGE
SDS-PAGE characterization of Enterotoxin E under reducing conditions. Lane M: Protein marker (kDa); Lane ETE-C: Purified Enterotoxin E Recombinant Monoclonal (Product # MA566520). Enterotoxin E showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-316.
产品信息
MA566520
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8F3
抗原
Enterotoxin E.
偶联物
形式
Liquid
浓度
4.9 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Enterotoxin E is a type of exotoxin produced by certain strains of Staphylococcus aureus, a bacterium commonly associated with food poisoning. This enterotoxin is part of a broader group of staphylococcal enterotoxins (SEs) that include enterotoxins A, B, C, D, and E, each responsible for triggering immune responses leading to gastroenteritis. Enterotoxin E, like its counterparts, is a heat-stable protein that can withstand cooking temperatures, making it a significant food safety concern when S. aureus contaminates food products. It functions by acting as a superantigen, binding directly to major histocompatibility complex (MHC) class II molecules on antigen-presenting cells and T-cell receptors, leading to massive T-cell activation and cytokine release independent of antigen specificity. This excessive immune activation causes symptoms such as vomiting and diarrhea typically within a few hours of ingestion. Enterotoxin E's heat resistance and potent biological activity necessitate rigorous food handling and hygiene practices to prevent staphylococcal food poisoning outbreaks.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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