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Invitrogen
EphA3 Polyclonal Antibody
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产品信息
PA5-29904
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human Eph Receptor A3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Jurkat, Raji.
Predicted reactivity: Mouse (97%), Rat (96%), Pig (97%), Chicken (92%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands and receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EK4; EPH-like kinase 4; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; H TYRO4; HEK; Human embryo kinase; human embryo kinase 1; testicular tissue protein Li 64; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase TYRO4
基因别名: EK4; EPHA3; ETK; ETK1; HEK; HEK4; TYRO4
UniProt ID: (Human) P29320
Entrez Gene ID: (Human) 2042
cell adhesion
regulation of epithelial to mesenchymal transition
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine phosphorylation
regulation of actin cytoskeleton organization
regulation of GTPase activity
ephrin receptor signaling pathway
regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
cellular response to retinoic acid
fasciculation of sensory neuron axon
fasciculation of motor neuron axon
